Tame the Beast
Harnessing The Power Of AI
We utilized AI-assisted image creation to bring to life a campaign idea for an AOR pitch. The pitch was for a drug (called “Product X Acoramidis”) that treated a disease called ATTR-CM. Later, we used the artwork for concept market research, where it allowed us to gauge the impact and stopping power of the idea and execution. AI played a pivotal role in transforming our creative execution of a concept, allowing us to bring the concept to life with unprecedented speed, precision, and visual style.
Mastering the art of AI prompting, we navigated complex terms like seeds, aspect ratios, and stable diffusion to perfect the visual style. Using MidJourney, we generated high-fidelity visuals of a bull at rest in a fragile china shop. We needed to capture the balance of raw power and controlled strength that embodied the disease (ATTR-CM) and the treatment we were advertising. ChatGPT was key in helping us craft AI-ready prompts that made the process efficient and seamless.
Leveraging AI allowed us to rapidly prototype and refine our creative assets, significantly reducing production timelines. Traditional illustration wouldn’t have done the concept justice, and CGI was simply not feasible within our tight timeframe of a pitch. AI empowered us to dynamically create visuals with the stopping power necessary to engage both the clients in the pitch meeting and healthcare professionals in our market research. The result was a campaign that seamlessly fused the artistry of AI with storytelling, delivering an emotionally charged concept that truly “Tamed the Beast.”
Background
The challenge we faced was conveying the severity and complexity of ATTR-CM in a way that was both emotionally compelling and easy to understand. The disease is chaotic, destructive, and relentless, often going unnoticed until it’s too late. We needed to create a campaign that educated the audience about its devastating effects on the heart, while also highlighting the transformative power of our treatment in a way that felt both impactful and memorable.
Acoramidis, a potential breakthrough for ATTR-CM, faced significant hurdles in gaining traction against entrenched competitors, and insights from our research showed that cardiologists needed compelling, data-driven storytelling that balanced emotional and rational appeals. This is where AI played a pivotal role. With an extremely tight turnaround, traditional methods would have been too slow, so we turned to MidJourney and ChatGPT to generate high-fidelity visuals and refine prompting. AI allowed us to rapidly prototype, craft impactful imagery, and fine-tune our prompting, all while ensuring the campaign stood out visually and emotionally.
We knew market research audiences, including HCPs, often process photorealistic images faster than stylized illustrations, leading to quicker understanding and stronger initial reactions. Concepts with rich textural detail invite viewers to linger and explore the visuals, increasing engagement. So we turned to Midjourney to see how we could elevate our stimuli closer to what a final ad may look like.

The Idea
We developed a bold branded campaign for ATTR-CM, using the striking metaphor of a bull in a china shop. The bull, representing the relentless and destructive nature of the disease, was depicted at rest—symbolizing how our treatment works to “Tame the Beast.” The fragile china shop mirrored the delicate TTR proteins breaking down in the heart, creating a powerful visual that captured both the essence of the disease and the promise of our treatment. This metaphor resonated deeply and helped us win a major piece of business, leaving a lasting impact on both the industry and our audience.
A great idea needs equally compelling visuals to make it stick. Our creative approach leveraged AI to craft a high-quality visual narrative that captured the emotional and scientific aspects of Acoramidis’ positioning. Using MidJourney, we developed illustrations that embodied the themes of stability, mastery, and heroism—key motivators for cardiologists. The ability to rapidly prototype and refine visuals ensured that the pitch not only had the necessary stopping power but also told a compelling, immersive story. This AI-assisted execution made the concept come alive in a way that engaged both clients and healthcare professionals, ensuring the campaign stood out and left a lasting impression.
Ensuring the campaign stood out and left a lasting impression.

Insights & Strategy
Our insight was grounded in the deep understanding that cardiologists are driven by a sense of purpose—they want to feel like heroes, making a real difference in their patients’ lives. However, we knew that depicting them directly in the ad could come off as cliché and fail to connect meaningfully. Instead, we tapped into their desire to take control and combat a seemingly insurmountable challenge. By using the “Tame the Beast” metaphor, we framed the disease itself—ATTR-CM and the TTR protein—as the beast that needs taming, giving HCPs the feeling they hold the power to conquer it. Our strategy empowered HCPs without showing them overtly, positioning them as the unsung heroes who harness the power of our treatment to control the chaos of the disease. The result was a campaign that spoke directly to their sense of purpose, showcasing the transformative potential of our drug in a fresh, compelling way.
Understanding that HCPs are bombarded with information daily, we knew visual impact was crucial to breaking through. Research emphasized that cardiologists operate in a world of chaos, spending only 28% of their time on direct patient care while managing a heavy workload. Our strategy used this insight by ensuring every visual and message reinforced Acoramidis as a stabilizing force, both scientifically and in practice. AI-generated visuals were the perfect balance of craft and efficiency. With MidJourney, we rapidly generated multiple executions, refining them to ensure the final visuals were scientifically credible, emotionally engaging, and strategically aligned with HCP behavioral drivers. This approach not only helped us break through the noise but also made the campaign resonate deeply with the audience.

Results
The campaign generated significant engagement and positive feedback from healthcare professionals, resonating deeply with its powerful metaphor and emotional tone. It successfully elevated awareness of ATTR-CM, positioning the treatment as a transformative solution and solidifying our brand’s impact in the market. The use of AI-powered creative execution played a key role in winning the AOR business, showcasing the innovative potential of AI in delivering high-quality work under tight time constraints. By seamlessly integrating AI into our workflow, we created a pitch that not only stood out but also demonstrated both cutting-edge technology and exceptional craft.



